The 2025 Omloop Het Nieuwsblad was the 20th edition of the Omloop Het Nieuwsblad road cycling one day race, which was held on 1 March 2025 as part of the 2025 UCI Women's World Tour calendar.
The race was won by Belgian rider Lotte Claes of Arkéa–B&B Hotels Women, after an early breakaway stayed away from the main field. 
Teams.
Fifteen UCI Women's WorldTeams, six UCI Women's ProTeams, and three UCI Women's Continental Teams made up the twenty-four teams that participated in the race.
UCI Women's WorldTeams
UCI Women's ProTeams
UCI Women's Continental Teams