The 2025–26 Mid-American Conference women's basketball season will be the season for Mid-American Conference women's basketball teams. It will begin with practices in October 2024, followed by the start of the 2025–26 NCAA Division I women's basketball season in November. Conference play will begin in January 2026 and conclude in March 2026. The 2026 MAC tournament will be held at Rocket Arena in Cleveland, Ohio for the 26th consecutive season. This season marks the conference's first change in membership since 2005 with the addition of UMass. It will also be the last MAC season for Northern Illinois, which will rejoin the Horizon League in 2026 after a nearly 30-year absence.
Head coaches.
Coaching changes.
Buffalo.
After a 30 win season, a WNIT Championship, and a 61–37 record at Buffalo over three seasons, Becky Burke was hired as the head coach at Arizona on April 14, 2025. On April 18, Buffalo hired Kristen Sharkey, former Buffalo basketball player and assistant coach, as the school's 14th women's basketball head coach.
Northern Illinois.
Lisa Carlsen resigned from as the Northern Illinois women's basketball coach on March 10, 2025 after a 13–17 season and a overall 147-155 record over nine seasons with the Huskies. On April 1, NIU hired Buffalo associate head coach Jacey Brooks as the new head coach.
Western Michigan.
Shane Clipfell announced his retirement from coaching on March 17, 2025 after 13 seasons and a 184–209 record as the head coach of Western Michigan University. On March 28, Detroit Mercy head coach Kate Achter was named the seventh head coach in program history.
Coaches.
"Notes:" 
Source: