The 1975 West Texas State Buffaloes football team was an American football team that represented West Texas State University (now known as West Texas A&M University) as a member of the Missouri Valley Conference (MVC) during the 1975 NCAA Division I football season. In their fifth year under head coach Gene Mayfield, the Buffaloes compiled an overall record of 5–6 with a mark of 2–2 in conference play, tying for second place in the MVC.