Herb-induced liver injury (HILI) is a form of drug-induced liver injury caused by herbal medicines, typically herbal supplements or herb-based ethnomedicines. Prevalence. Herbs are a common component of ethnomedicines and their potential hepatotoxicity is a concern for people taking such medicines or other herbal supplements. Use of such products is widespread within Ayurvedic medicine. Although injury from ayurvedic medicines has commonly been blamed on improper adulteration of drugs, a number of preparations can be harmful though direct effects purely because of their herbal ingredients.