The mixed 4 × 50 metre medley relay event at the 2024 World Aquatics Swimming Championships (25 m) was held on 11 December 2024 at the Duna Arena in Budapest, Hungary. Records. Prior to the competition, the existing world and championship records were as follows. Background. The United States entered without three members of their 2022 world record-setting team, relying on Michael Andrew for breaststroke and Regan Smith and Katherine Berkoff to fill other legs. Italy also fielded a changed lineup, with Lorenzo Mora and Silvia Di Pietro returning, and Simone Cerasuolo joining. Canada returned with key names including Kylie Masse and Ilya Kharun. Great Britain fielded an entirely new team, and China and Australia were led by Qin Haiyang and Isaac Cooper respectively. The Netherlands returned most of their relay, and the Neutral Athletes B team featured Russian athletes Miron Lifintsev, Kirill Prigoda, and Arina Surkova. "SwimSwam" wrote that predicting the winners of the mixed relays was "nigh impossible" due to the amount of variables. They predicted the Neutral Athletes B team would win, the USA would come second and Italy would come third. Results. Heats. The heats were started at 11:07. Final. The final was held at 19:06.