The 2025 Abruzzo Open Francavilla al Mare was a professional tennis tournament played on clay courts. It was the seventh edition of the tournament which was part of the 2025 ATP Challenger Tour. It took place in Francavilla al Mare, Italy between 5 and 11 May 2025.
Singles main-draw entrants.
Other entrants.
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw through the Junior Accelerator Programme:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw: