Mathieu Darnaud (; born 11 July 1975) is a French politician who has presided over the Senate Republicans since 1 October 2024. A member of The Republicans (LR), he has been a Senator for Ardèche since 2014. He served as First Vice President under Senate President Gérard Larcher in 2023 and 2024.
Darnaud previously served as Mayor of Guilherand-Granges, Ardèche (2008–2017) and a member of the Regional Council of Rhône-Alpes (2010–2014). In 2014 and 2015, he presided over the "communauté de communes" Rhône Crussol, seated in Guilherand-Granges.