Lancotrione is a herbicide, closely related to tefuryltrione. Its mode of action inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme which produces homogentisic acid.
It was announced by Ishihara Sangyo Kaisha in 2016, and commercialised in 2019. Lancotrione is a new herbicide, usually used in the form of sodium salt to control grass weeds, in rice crops. As such, little is yet known about it.