The 2024–25 SIU Edwardsville Cougars women's basketball team represented Southern Illinois University Edwardsville during the 2024–25 NCAA Division I women's basketball season. The Cougars, who were led by fourth-year head coach Samantha Quigley Smith, played their home games at the First Community Arena in Edwardsville, Illinois as members of the Ohio Valley Conference.
Previous season.
The Cougars finished the 2023–24 season 5–26, 2–16 in OVC play, to finish in last place. They failed to qualify for the OVC tournament, as only the top eight teams qualify for the tournament.
Preseason.
On October 16, 2024, the OVC released their preseason coaches poll. SIU Edwardsville was picked to finish tied for eighth place in the OVC regular season.
Preseason rankings.
Source:
Players to Watch.
Each OVC team selected two "Players to Watch" for their team.
Source:
Schedule and results.
!colspan=12 style="| Exhibition
!colspan=12 style="| Non-conference regular season
!colspan=12 style=""| OVC regular season
Sources: