The Port of Mazatlán is a port located on Mexico's Pacific coast in the state of Sinaloa, at the entrance to the Gulf of California. Description. One of Mexico's largest ports, Mazatlán is also the largest fishing port on the west coast. It handles Ro-Ro, dry and liquid bulk, passengers, fish, containers and general cargo. Two international shipping lines, Mediterranean Shipping Company and Hapag-Lloyd, operate in the port.