The 2012 IUP Crimson Hawks football team was an American football team that represented Indiana University of Pennsylvania (IUP) of Indiana, Pennsylvania, as a member of the Pennsylvania State Athletic Conference (PSAC) West Division during the 2012 NCAA Division II football season. In their second season under head coach Curt Cignetti, the Crimson Howls compiled a 12–2 overall record, 6–1 in conference, won the PSAC championship, made it to the NCAA Division II Quarterfinal where they fell to Winston-Salem State 21–17, and outscored their opponents 471 to 175.
The team gained 3,630 rushing yards and 2,215 passing yards. On defense, they gave up 1,121 rushing yards and 2,489 passing yards. The team's individual leaders included:
The team's wide receivers coach was former NFL player Rod Rutherford.
The team played its home games at Miller Stadium in Indiana, Pennsylvania.