The 2024–25 Campionato Sammarinese di Calcio is the 40th season of league competition in San Marino, in which the country's 15 amateur football teams and the San Marino Academy U22 compete. The season began on 30 August 2024.
The winners qualify for the 2025–26 UEFA Champions League first qualifying round. The Conference League play-off and 2024–25 Coppa Titano winners qualify for the 2025–26 UEFA Conference League first qualifying round.
First phase.
League table.
<onlyinclude>
</onlyinclude>
Conference League play-off.
Teams placed 2nd-11th qualify for the Conference League play-off, with the winners earning the second and final place in the Conference League first qualifying round.
Bracket.
First round.
Teams placed 8th-11th entered the first round; teams placed 2nd-7th received a bye.
!colspan="3" align="center"|
Quarter-finals.
The two first round winners and teams placed 2nd-7th entered the quarter-finals, held over two legs. The first legs were held on 3–4 May 2025, followed by the second legs on 6–7 May 2025.
Semi-finals.
The four quarter-final winners entered the semi-finals, held over two legs. The first legs were held on 10 May, followed by the second legs on 14 May.
Final.
The final was held between the two semi-final winners.